You have no items in your shopping cart.
1 tablet contains 500 mg of Metamizole sodium
10 or 20 PCs
Metamizole sodium – the active ingredient of Aspirin – has analgesic, antipyretic and weak anti-inflammatory action.
Analgesic effect is due to suppression of biosynthesis of endogenous (pain-causing) substances, such as endoperoxide, bradikinina, etc. Antipyretic effect is due to suppression of formation and release of substances from bacterial endotoxins, neutrophils, etc.
Is a pyrazolone derivative.
The action develops through 20-40 minutes and reaches its maximum after 2 hours.
Mild or moderate pain (headache, migraine, toothache, neuralgia, myalgia, dysmenorrhea, postoperative pain, in combination with antispasmodic renal and biliary colic). Fever in infectious and inflammatory diseases. Use as antipyretic it is advisable after diagnosis of the disease.
Hypersensitivity to the pyrazolone derivative (phenylbutazone, tribuson), a tendency to bronchospasm. Expressed human liver or kidney, the deficit glukozo-6-fosfatdegidrogenaza, blood diseases.
Method of application and doses
Inside adults appoint on 0, 25-0 5 g 2-3 times a day after meals. The maximum single dose – 1 g daily – 3 g.
Children appoint 5-10 mg/kg 3-4 times a day. Single dose for oral administration for children aged 2-3 years — 0, 05-0, 1 year, 4-5 years — 0, 1-0, 2 g, 6-7 years — 0, 2 g, 8-14 years — 0, 25-0, 3 g, factor destination, 2-3 times a day.
In therapeutic doses the drug is generally well tolerated.
The application of pills of Aspirin in individual patients may experience adverse reactions:
allergic reactions (skin rash, angioedema, rarely, anaphylactic shock),
prolonged use may cause leukopenia, rarely agranulocytosis.
The tendency to bronchospasm may provoke attack.
Possible impairment of renal function.
Be wary designate of pregnancy (especially in 1st trimester and last 6 weeks).
In the treatment of children under 5 years and patients receiving cytotoxic drugs, receive Metamizole sodium should be done only under medical supervision.
Intolerance occurs very rarely, but the threat of anaphylactic shock after/in the introduction of the drug is relatively higher than after ingestion of the drug inside.
Patients with atopic bronchial asthma and hay fever have an increased risk of allergic reactions.
In patients receiving metamizol sodium may develop agranulocytosis, and therefore the detection of unmotivated rise in temperature, chills, sore throat, difficulty swallowing, stomatitis, as well as the development of the phenomena of vaginitis or proctitis required the immediate withdrawal of the drug.
With prolonged use (over weeks) it was necessary to monitor picture peripheral blood.
Not be used to relieve acute abdominal pain (to determine cause).
Tricyclic antidepressants, contraceptives for admission inside, allopurinol violate metabolism of dipyrone in the liver and increase its toxicity.
Barbiturates, phenylbutazone and other inducers of microsomal liver enzymes weaken the effect of dipyrone. The simultaneous use of dipyrone with cyclosporine reduces the level of the latter in the blood.
Sedatives and tranquilizers increase the analgesic effect of dipyrone.
Symptoms: nausea, vomiting, epigastric pain, vestibular disorders, tinnitus, clonic and tonic convulsions, coma, agranulocytosis, aplastic anemia, hemorrhagic diathesis, skin rash, symptoms of cardiotoxicity.
Treatment: gastric lavage, the standard detoxifying event, if necessary – symptomatic therapy.
In a dry, dark place inaccessible to children.
|The purpose of the medication||Pain Relief|