Modelle PRO - Monophasic oral contraceptive with anti-mineralocorticoid and anti-androgenic properties.The contraceptive effect of combined oral contraceptives is based on the interaction of various factors, the most important of which are the suppression of ovulation and changes in the properties of the cervical secretion, as a result of which it becomes less permeable to sperm.If used correctly, the Pearl Index (the number of pregnancies per 100 women per year) is less than 1. If you skip pills or use it incorrectly, the Pearl Index may increase.In women taking combined oral contraceptives, the menstrual cycle becomes more regular, less frequent painful menstruation, decreases the intensity of bleeding, which reduces the risk of anemia. In addition, according to epidemiological studies, the use of combined oral contraceptives reduces the risk of developing endometrial cancer and ovarian cancer.Drospirenone contained in the drug Modelle PRO, has antimineralocorticoid action. Prevents weight gain and edema associated with estrogen-induced fluid retention, which ensures a very good tolerability of the drug. Drospirenone has a positive effect on premenstrual syndrome (PMS). Clinical efficacy of Jess in alleviating the symptoms of severe PMS, such as severe psycho-emotional disorders, breast engorgement, headache, muscle and joint pain, weight gain, and other symptoms associated with the menstrual cycle, is shown.Drospirenone also has antiandrogenic activity and helps reduce acne, oily skin and hair. This action of drospirenone is similar to the action of natural progesterone produced by the body.Drospirenone does not have androgenic, estrogenic, glucocorticoid and antiglucocorticoid activity. All this combination with anti-mineralocorticoid and anti-androgenic effects provides Drospirenone with a biochemical and pharmacological profile similar to natural progesterone.