PANAVIR (Panavir®)☆

Clinical Pharmacology

Panavir - purified extract of the shoots of the plant Solanum tuberosum; The main active ingredient is hexose glycoside, consisting of glucose, rhamnose, arabinose, mannose, xylose, galactose, and uronic acids.

Panavir is an antiviral and immunomodulatory agent. Increases the body’s non-specific resistance to various infections and contributes to the induction of interferon alpha and gamma leukocytes in the blood.

At therapeutic doses, the drug is well tolerated.

Tests have shown the absence of mutagenic, teratogenic, carcinogenic, allergenic and embryotoxic action. In preclinical studies on laboratory animals, negative effects on reproductive function and fetal development have not been established.

It has anti-inflammatory properties in experimental models of exudative edema, chronic proliferative inflammation and in the pseudo-allergic inflammatory test for concanavalin A.

An analgesic effect was shown on models of neurogenic pain and pain caused by inflammation and thermal irritation.

It has antipyretic effect.

On the model of parkinsonian syndrome caused by systemic administration of neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, neuroprotective properties are shown.

It has the ability to improve the function of the retina and optic nerve.

It has wound healing properties in terms of the model of gastric ulcer.

Indications

In the complex treatment of tick-borne encephalitis (reduction of viral load and removal of neurological symptoms, including anisoreflexia, reduced reflexes, painful exit points of the cranial nerves, nystagmus)

As part of complex therapy: herpes virus infections of various localization (including recurrent genital herpes, Herpes zoster and ophthalmic herpes).

Reduced immunity in combination with infectious diseases.

Cytomegalovirus infection in combination with habitual miscarriage.

In the complex therapy: human papillomavirus infection (anogenital warts).

Composition

Vaginal suppositories1 supp. active ingredient: Panavir (Solanum tuberosum shoots polysaccharides) 200 mcg

Excipients: polyethylene oxide 1500 (macrogol 1500) - 1.2599 g; polyethylene oxide 400 (macrogol 400) - 0.1399 g

Panavir is marketed under different brands and generic names, and comes in different dosage forms:

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