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One milliliter of drops for oral administration contains 50 mg of the polymaltose complex of ferric trivalent iron hydroside + sodium propylparahydroxybenzoate, water, cream flavor, sodium methyl parahydroxybenzoate, sodium hydroxide, sucrose. In terms of iron, in one drop of the solution is 2.5 mg.Syrup Maltofer (1 ml) contains: 10 mg of polymetal iron complex + auxiliary substances (propyl parahydroxybenzoate, sorbitol solution 70%, water, cream flavor, methyl parahydroxybenzoate, sodium hydroxide, 96% ethanol, sucrose).One tablet contains: iron 100 mg + additional ingredients (vanillin, talc, chocolate flavor, microcellulose, dextrates, sodium cyclamate, macrogol 6000, cocoa powder).On one ml of the solution for ingestion is 20 mg of iron (in the form of a polymetose complex of ferric hydroxide) + auxiliary substances (sodium propylparahydroxybenzoate, sorbitol 70% rr, sucrose, sodium methylpahydroxybenzoate, sodium hydroxide, water, flavor).In one ml of the solution for the / m administration contains 141 to 182 mg of iron hydroxide (50 mg ferric hydroxide) plus water for injection, sodium hydroxide, hydrochloric acid.
Drops Maltofer for ingestion - a liquid of dark brown color, with a creamy taste. The drug in drops is available in 30 ml, in vials with a dispenser.    Brown syrup has a viscous consistency, is available in 150 ml vials, with a measuring cup.    Means in the form of tablets - in the form of flat cylinders. Color - brown, with white inclusions and risk. Blisters for 10 pieces, packs of 3 blisters.    The solution for oral administration also has a dark brown color.    The solution for intramuscular administration has a brown color, is issued in ampoules of 2 ml, in cardboard packs of 5 ampoules.pharmachologic effect
The preparation of iron replenishing its deficiency in the body.
Iron - a very important and necessary for the body element. It is a part of hemoglobin and myoglobin, it performs a number of important functions in the metabolism process. Deficiency of iron leads to anemia.Due to the fact that the polymetal complex is more stable and practically does not enter the oxidation reaction, iron is not released into the digestive tract as Fe3 + ions. Its structure is most similar to the natural structural element - ferritin. Due to this, the frequency and the number of possible side effects from taking the drug is significantly reduced.Reduces the degree of susceptibility to oxidation of low and very low density lipoproteins.Getting into the systemic bloodstream, by sucking into the intestine (in the duodenum or small intestine) or by direct injection (injection solution), iron passes through the reticuloendothelial system and accumulates in the liver. And then, in the bone marrow, it participates in the processes of formation of hemoglobin, myoglobin and other elements.Studies were carried out using the technique of double isotopes, which showed that the degree of assimilation of iron is selective. If a sufficient amount of substance is present in the body, then the degree of absorption will be extremely low, in comparison with the state of iron deficiency. The stronger the body lacks iron, the more it absorbs.The product has a low toxicity. Unused iron is excreted with feces, dead cells of the epithelium of the gastrointestinal tract and skin, during breathing, with bile and urine. It should be remembered that in women there is a large loss of iron during menstruation.If it is not possible to use the drug in tablets or another form, an injectable solution is used. When intravenously administered one day after the injection, the drug reaches the maximum concentration in the plasma.
The remedy is used:    for the treatment and prevention of iron deficiency anemia, clearly not showing a lack of iron    to prevent people on a strict diet, the elderly, pregnant women, children and adolescents during periods of active growth.Injection of the drug can be used only after confirming the lack of iron by examining the blood composition (hemoglobin level in the blood, red blood cells, hematocrit, serum ferritin).
The drug is contraindicated:    in the presence of hypersensitivity reactions    bone marrow hypoplasia    with chronic polyarthritis    hemochromatosis, hemosiderosis    the Osler-Randu-Weber Syndrome    when erythropoiesis is disturbed    with sideroahrestic anemia, lead anemia, porphyria of the skin, thalassemia    with uncompensated liver cirrhosis and kidney disease in acute, late stages    with stenosis or other diseases of the digestive tract    with regular blood transfusions.In the presence of diseases of the gastrointestinal tract, a solution for intramuscular injections is often used. It can not be used for intravenous administration, in the first trimester of pregnancy, for children up to 4 months. Otherwise, contraindications remain the same as for oral forms.
pain in the epigastric region, nausea, diarrhea, constipation, vomiting    urticaria, eczema, anaphylactic reactions    rarely, the enamel stains black.Solution for injection, adverse reactions:
arthralgia    fever and swollen lymph nodes    dyspepsia    allergic reactions    headache.If the injection has been done incorrectly, the skin may change color, inflammation and pain occur at the site of administration of the remedy.
The regimen, dosage and duration of treatment are determined by the attending physician.Drops, syrup, tablets or a solution are taken orally during or after a meal. Tablets can be cracked or chewed, liquids can be diluted in juice or water.
for premature infants is 1-2 drops, based on one kilogram of body weight, the course of treatment is 3-5 months    for children up to a year - from 10 to 20 drops per day    for children from one year to 12 years - from 20 to 40 drops per day    adults, pregnant women and children over 12 take 40-120 drops a day.In the presence of latent iron deficiency and for prevention:
Children up to a year are prescribed 6 to 10 drops per day    children from one year to 12 years - 10-20 drops    adults and pregnant women from 20 to 40 drops per day.Instructions for syrup
With anemia:    Children up to a year appoint 2.5-5 ml of syrup per day    from year to 12 - 5 or 10 ml    adults, pregnant women - 10 to 30 ml per day.According to the instructions for tablets, Maltofer Viefort, daily dosage for adults with iron deficiency anemia - 1-3 pieces per day. For the prevention or treatment of latent iron deficiency, appoint one tablet a day. Pregnant women take 2-3 tablets a day as part of the treatment.
In order to normalize the level of hemoglobin in the blood (for adults) one bottle of the drug is drunk 1 or 3 times a day. The course is from 3 to 5 months, then the dosage is reduced to 1 bottle. For prophylaxis take 1 bottle a few months. For pregnant women, the dosage will be slightly higher.
The daily dosage and duration of treatment should be determined by the physician. They are calculated according to the weight of the patient according to special tables (according to the formula).Before the first dose, a sensitivity test should be performed. Intramuscularly injected half or a quarter of a single dose. In the absence of any side effects, the remaining liquid in the syringe is injected.Typically, for adults, the daily dosage is one ampoule of the solution. The maximum amount of medication administered during the day:    for children weighing up to 5 kg - the fourth part of the ampoule    for children weighing from 5 to 10 kg - half the ampoule    10-50 kg - one ampoule    for adults - two ampoules.If after 2 weeks of application there is no improvement in hemodynamic parameters, it is necessary to correct the treatment and revise the diagnosis.Instead of the usual method of drug administration, it is recommended that the ventro-gluteal technique. The needle should be thin, not more than 6 cm in length. After the injection, it is recommended to walk a little or move your foot to disperse blood (with medicine) through the body.
The likelihood of an overdose is extremely small, especially when taken orally. No cases of overdose have been reported. Clinical studies have confirmed that even with the intake of 2000 mg of iron per kg of human weight, a lethal outcome is unlikely.The likelihood of an overdose increases with intramuscular injection of the drug. There can be an acute overload with iron, symptoms of hemosiderosis will appear.Therapy - according to the manifested symptoms, the reception of chelates (Deferoxamine intravenously).
Antacids, vitamin E, eggs, milk, coffee and black tea, cheeses and some cereals can complicate the process of iron absorption in the intestine. Citric acid and vitamin C, on the contrary, strengthen the process.Plasma concentrations of penicillamine, tetracycline and sulfasalazine are reduced by the action of iron salts.Storage conditions
Keep out of direct sunlight, keep away from light and from children. Temperature regime: up to 25 degrees.Shelf life - 5 years. Ampoules should be used immediately after opening.
The drug (especially the form for oral use) can stain the feces black.Care should be taken in patients with diabetes mellitus or with intolerance to fructose.The drug is not recommended for patients with leukemia.Ampoules with the drug should not contain sediment or be damaged. After opening, the injection solution should be used immediately.Intramuscular administration of the drug to children younger than 4 months is not recommended.
For children under 12 years, the most appropriate is the use of a syrup. At the age of up to one year, it is recommended that syrup be changed to drops for children.The drug has positive feedback when taking children, the drug is well absorbed, practically does not cause adverse reactions.
There have been studies confirming that in women in the 2nd and 3rd trimester of pregnancy, taking the drug does not cause illness of the mother or fetus.Reviews during pregnancy on the medicine are good. The drug well raises hemoglobin, rarely causes adverse reactions. If there is an urgent need to use the product during lactation, you should consult with your doctor about the advisability of continuing to breast-feed.
The drug helps to raise low hemoglobin in a relatively short time. The medicine has, basically, positive reviews. Side effects occur rarely, most often it is diarrhea or constipation. Some people do not like the unpleasant taste of syrup or drops, unlike the smell. After injections with a remedy with the wrong technique of administration, sometimes dark spots remain on the skin, which last a long time.Reviews for babies
Maltofer quickly and effectively raises hemoglobin to small and nursing infants. Parents give preference to drops or fluids for oral administration. Often diluted with milk. Side effects occur infrequently.
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