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Gestodene 0.075 mg and ethinyl estradiol 0.02 mg, lactose monohydrate, corn starch, povidone, magnesium stearate as adjuvants
Combined estrogen-progestational medication
Monophasic combination drug, which inhibits the secretion of gonadotropic hormones, inhibits maturation of follicles and inhibits ovulation. The hormonal substances in the composition increase the viscosity of the vaginal mucus and cervical canal and change the endometrium, which prevents the penetration of spermatozoa into the cervical canal, on the one hand, and reduces the likelihood of implantation of the oocyte, on the other. Affect the movement of spermatozoa in the fallopian tubes.Pharmacokinetics
Gestodene after absorption is rapidly absorbed and after 1 hour in the blood its maximum content is noted. In blood, it binds to albumin and a special globulin (GSHG) by 69%. With daily intake, the content of Gestodene in the blood increases by 4 times. During the reception of the second half of the tablets, the equilibrium state of its level in the blood is noted, the decrease of which occurs biphasic. Gestodenum is completely metabolized and in the form of metabolites is excreted in urine and bile (half-life of 24 hours).Ethinyl estradiol is also completely absorbed from the intestine. Peak of its content in the serum after 1-2 hours. Reduction in the level of the substance in the blood occurs in two phases. Ethinyl estradiol in the form of metabolites is excreted by bile and urine. The equilibrium concentration is reached after 5-6 days from the beginning of the drug intake.Indications for use
angina pectoris, hypertension, myocardial infarction    cerebrovascular accident in the anamnesis, including transient    presence of risk factors for thrombosis    diabetes mellitus, complicated by vascular lesions    pancreatitis    severe liver and kidney disease    decreased blood clotting    hormone-dependent breast tumors    anticipated pregnancy    bleeding from the genital tract of unclear etiology    epilepsy    vascular thrombosis of the retina    thrombosis of the veins of the limbs    overweight    hypersensitivity to gestodene or ethinylestradiol.
Low-dose hormonal contraceptives (containing minimal doses of estrogens and progesterone) are less likely than high-dose hormones to cause adverse reactions, but they need to be known:    soreness and enlargement of the mammary glands, discharge from them    bloody discharge and uterine bleeding    changes in vaginal secretion    depression, fatigue, headache (in the first months of use)    abdominal pain, nausea and vomiting    impaired vision    rash, multiforme and nodosum erythema, itching    acne, alopecia    jaundice    swelling and weight gain    development of thrombosis and thromboembolism.Since the use of hormonal contraceptives causes side effects, the appointment is made only by a doctor after a thorough examination and determine the "benefit-risk" of their use. After the drug is canceled, the menstrual cycle is restored. Pregnancy after the cancellation of Logest occurs within a year.
Tablets are taken orally every day, in the order indicated on the package, preferably at the same time, without interruption for 21 days. Then there is a break of 7 days, during which bleeding occurs, then go on to receive new tablets.If a woman did not take hormonal contraceptives earlierThe reception begins on the first day of the menstrual cycle. If the reception is started on days 2 to 4, it is necessary to use barrier contraception for the first week of taking the tablets.Transition from other combined contraceptives
It is necessary to immediately start taking this contraceptive after taking an active pill of the previous hormonal contraceptive.In the transition from intrauterine hormonal contraception containing progestogen, intradermal implants and injections, mini-piliThis drug is taken any day after the end of the mini-drink. When using injections or implants, the first tablet is taken on the day of removal of the intradermal implant or the end of the contraceptive injection. However, in all cases within a week, barrier contraception is prescribed.How to take the drug after an abortion in the early stages
The drug is used immediately. In this case, there is no need for additional contraception.Birth control pills after childbirth or abortion in late pregnancyAdopted on the 21-28 day after the physiological birth (or induced abortion, conducted in the second trimester). In the case of a later onset, a barrier method of contraception is used during the week.If you miss the tablet, there is a separate instruction for using Logest.
Conditions that are serious for health or life are not known. At excess of a dose - a vomiting, a nausea, neobylnoe a bleeding from sexual ways.
There is a decrease in contraceptive protection when taking ampicillins and tetracyclines, as they reduce the circulation of estrogens in the liver, lowering the concentration of ethinyl estradiol.Sulfonamides, butadione, analgin, amidopirin increase the metabolism of steroid hormones that make up Logesta.Medicines: barbiturates, carbamazepine, ritonavir, rifampicin, oxcarbazepine, griseofulvin reduce the contraceptive efficacy of Logest.Combined contraceptives affect the metabolism of cyclosporine, leading to a decrease in its concentration in the plasma. Admission of estrogen-progestogen means requires correction of dosing of sugar-reducing drugs, as well as indirect anticoagulants.Storage conditions
Store in a dry place. Storage temperature not higher than 20 ° C.Shelf life - 3 years.
Womens reviews of Logest indicate that the use of the drug is characterized by high reliability. Drug tolerance is estimated as very good. Women note that taking the drug does not affect body weight, even with long-term use. There is also no androgenic effect on the skin and hair growth.The doctors' comments indicate a positive clinical characteristic of the drug. Reducing the dose of hormones significantly reduces the number of side effects. At the same time, the drug has a high bioavailability, which allows you to predict its level in the blood and apply it in a lower dose. There is a lower risk of intermenstrual bleeding when taking funds containing gestodene. Doctors appoint it to regulate the menstrual cycle. The drug is effective for profuse, long and painful menstruation. Against the background of its use, painful periods are observed less often, the intensity of secretions decreases, the risk of anemia decreases.Analyzing feedback on Logest in the forums, it can be concluded that Logest is recommended for women beginning to "get acquainted" with oral contraceptives. It is used for poor tolerability of high-dosage drugs. In addition, it is used to treat and prevent many gynecological diseases.From the shortcomings of the drug noted that it can not be taken with many medications (even with analgin), the appearance of cellulite. For many, the important point is the price. The high price of this drug is assessed as a drawback.'
|The purpose of the medication||Contraception|