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The preparation for external use. Belosalic® lotion has anti-inflammatory, antipruritic, antiedematous, antiallergic, antiproliferative, antiviral, keratolytic, antimicrobial, antifungal action.
Betamethasone dipropionate is a synthetic corticosteroids that has anti-inflammatory, antiallergic, antipruritic and vasoconstrictive effect. When applied to the surface of the skin constricts blood vessels, relieves itching, reduces the release of inflammatory mediators (eosinophils and mast cells), interleukins 1 and 2, interferon-gamma (lymphocytes and macrophages), and inhibits the activity of hyaluronidase and reduces the permeability of the vascular wall. Interacts with specific receptors in the cytoplasm of cells, stimulates the synthesis of mRNA, inducing the formation of proteins, including lipokortina, mediating cellular effects. Lipokortin inhibits phospholipase A2, inhibits the release of arachidonic acid and the biosynthesis endoperekisey, prostaglandins, leukotrienes (contributing to inflammation, allergies and other pathological processes).
Salicylic acid due to the keratolytic action cleans the lesion from the flakes, promotes the penetration of the betamethasone into the skin, maintains the acidic environment of the skin, preventing the development of bacterial and fungal infection.
Subacute and chronic dermatoses, sensitive to therapy, corticosteroids, and accompanied by hyperkeratosis and desquamation:
Application of pregnancy and breastfeeding
The use of the drug Belosalic® lotion in pregnant women is permitted in cases where the expected benefit to the mother outweighs risk to the fetus. In such cases, the use of the drug should be short and limited to small areas of the skin.
In the period of breastfeeding the drug Belosalic® lotion possible on the strict condition, but the drug should not be applied to the skin of the breast before feeding.
The preparation is intended for external use only.
Avoid contact with eyes and mucous membranes, and the use of the drug in the anogenital region.
Not recommended the use of the drug under occlusive dressing, except when it is necessary.
With the development of fungal or bacterial microflora on the skin, it is necessary the additional use of antibacterial or antifungal agents.
Drug Belosalic® lotion in the form of topical solution is especially suitable for use on the skin of the scalp. The solution is easily distributed on the surface of the skin, not pieces and dry hair, leaves no visible traces, has a cooling effect on the skin.
Effects on ability to drive vehicles and management mechanisms
Data about the adverse effects of the drug Belosalic® lotion on the ability to drive vehicles and mechanisms is not available.
1 g solution contains:
Active substances: betamethasone dipropionate 640 mcg, which corresponds to the contents of betamethasone – 500 µg salicylic acid – 20 mg.
Excipients: disodium edetate – 0.3 mg, hypromellose 4000 GPa – 5 mg, sodium hydroxide – 5 mg, isopropanol – 392 mg, water – 577,06 mg.
Method of application and doses
The preparation is intended for external use.
A few drops of the topical solution was spread evenly over the surface of the skin, gently rubbing. The multiplicity of application 2 times/day, in mild cases, a single use.
Duration of continuous treatment is usually limited to 3-4 weeks. If you need a longer course of treatment is recommended to use the drug less frequently, e.g., every other day.
The drug can be administered with caution in children 6 months and for the shortest possible time.
Side effects are usually reversible and are of a slight character.
With the skin: may develop hypersensitivity reactions (itching, burning, redness), acne-like changes, hypopigmentation, striae, skin atrophy, hypertrichosis, secondary infection of the skin.
While uncontrolled long-term continuous use, and when applied to large areas of skin: telangiectasia, systemic manifestations side effects of corticosteroids or salicylates.
With the development of hypersensitivity reactions or adverse reactions the drug should be discontinued and consult a doctor.
Not clinically significant interactions with other drugs.
Simultaneous use of cosmetic and dermatological topical products containing ethanol or medical Soaps with a strong drying effect can cause irritation of the skin.
Symptoms: manifestations of systemic side effects.
Treatment: advised removal of the drug and symptomatic therapy.
|The purpose of the medication||Corticosteroids|