Alpha D3 Teva caps 0.5mcg #60

Alpha D3 Teva

You can buy Alpha D3 Teva here

Composition

1 capsule of Alpha D3 contains 0.25, 0.5, 1.0 µg of alfacalcidol, citric acid, alpha-tocopherol, propyl gallate, ethanol, peanut oil, gelatin, glycerol, mannitol, anidsorb, sorbitan, ferric oxide yellow, black, red, titanium dioxide, water, ink is black.

Release form

Soft gelatin capsules, oval shape, brown-reddish in 0.25, 0.5, 1.0 μg. Alfacalcidol is applied to the capsules in black ink. Packing in blister number 10 3 blisters in a cardboard box or polypropylene container, cardboard box number 30, 60.

pharmachologic effect

Regulator of calcium-phosphorus metabolism, compensating for vitamin D deficiency.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Vitamin involved in the regulation of calcium-phosphorus metabolism. Increases the absorption of calcium and phosphorus in the intestine, enhances their reabsorption in the kidneys, reduces the content of parathyroid hormone in the blood, normalizes the calcium balance in the body. Actively affects the process of bone resorption, normalizes bone mineralization. Stimulates the synthesis of bone morphogenetic proteins, which increases its elasticity and reduces the frequency of bone fractures.Alfacalcidol normalizes the growth of muscle tissue and the differentiation of cells of different types improves coordination of movements, increases humoral and cellular immunity.The duration of the drug up to 48 hours.

Pharmacokinetics

The drug is rapidly absorbed from the gastrointestinal tract. After a single dose of the drug, its maximum concentration in the blood is determined after 12 hours.Metabolized to calcitriol, mainly in the liver, in bone tissue - significantly less. The kidneys do not biotransform. Excreted approximately in equal parts by the kidneys and with bile through the intestines. T1 / 2 —35 hours.

Indications for use

    conditions of the body that require an increased need for vitamin D (osteoporosis, osteomalacia, osteopathy against the background of renal failure)    prevention and treatment of vitamin D hypo- and avitaminosis    unbalanced or inadequate nutrition (vegetarian diet, parenteral nutrition)    lack of ultraviolet radiation    malabsorption    hypocalcemia with hypoparathyroidism    hereditary hypophosphatemia (rickets D-resistant)    liver failure    Fanconi syndrome, obstructive jaundice, cirrhosis of the liver    fast weight loss    multiple pregnancy (for health reasons).

Contraindications

    hypervitaminosis D    hypersensitivity to the drug    hypermagnesium    hypercalcemia    children under 3 years    pregnancy    lactation.To be used with caution in atherosclerosis, nephrolithiasis, renal failure, granulomatosis, active pulmonary tuberculosis, urolithiasis, heart failure.

Side effects

    heartburn, anorexia, dry mouth, nausea, vomiting, abdominal pain, diarrhea, constipation    fatigue, dizziness, drowsiness, headache, weakness    itching, skin rash    tachycardia    moderate pain in muscles, joints, bones    hypercalcemia, increased concentration of high density lipoproteins.

Instructions on Alpha D3-Teva (Method and Dosage)

Adults: take in the morning 1 time per day, inside. The duration of the course depends on the type of disease, the effectiveness of therapy and is determined individually.In diseases of the gastrointestinal tract, rickets and osteomalacia caused by vitamin D deficiency: 1-3 µg / day.In chronic renal failure, osteodystrophy: 0.25–2 µg / day.In the treatment of osteoporosis: 0.5–1 µg / day.Fanconi syndrome: 2–6 µg / day.With osteomalacia and hypophosphatemic rickets: 4–20 µg / day.When taking Alpha D3-Teva, in order to avoid the development of hypercalcemia, it is necessary to monitor calcium level in plasma and urine once a quarter, monitor the therapeutic effect of the drug and, if necessary, adjust the dose.With an increase in biochemical parameters (plasma alkaline phosphatase content), it is necessary to reduce the dose of the drug or cancel it before normalization, then therapy can be continued. Treatment should begin with the appointment of the minimum specified dose, and then the dose can be increased.Important: the instructions for use of Alpha D3-Teva should be strictly followed, otherwise overdose of the drug with the development of side effects is possible.

Overdose

Early symptoms characteristic of hypercalcemia (acute hypervitaminosis D): dry mouth, nausea, diarrhea, constipation, anorexia, vomiting, metallic taste, hypercalciuria, fatigue, headache, bone pain, general weakness, myalgia.Late symptoms of hypervitaminosis D: drowsiness, dizziness, heart rhythm disturbance, confusion, increased blood pressure, turbidity of the urine, conjunctival hyperemia, pruritus, nephrolithiasis, photophobia, gastralgia, pancreatitis, psychotic disorders, weight loss.With the development of chronic hypervitaminosis D, calcification of the kidneys, lungs and soft tissues, blood vessels, as well as renal failure is observed.In the early stage of the onset of symptoms of acute overdose, it is necessary to stop taking Alpha D3-Teva, flush the stomach. In severe cases, hydration is carried out with infusion saline solutions with monitoring of the state of the heart and kidney function.

Interaction

Alfacalcidol in the treatment of osteoporosis can be administered simultaneously with estrogen and drugs that suppress bone resorption. Inducers of liver enzymes (Phenobarbital and phenytoin) reduce the concentration of alfacalcidol in the blood, and inhibitors, on the contrary, increase the concentration (at the same time, it may decrease its effectiveness). With the simultaneous appointment with the preparations of digitalis dramatically increases the risk of arrhythmias.When combined with mineral oil, decreases its absorption (for a long time). Alfacalcidol increases the absorption of drugs containing phosphorus and increases the risk of hyperphosphatemia. Simultaneous administration with thiazide diuretics and calcium-containing drugs can cause hypercalcemia.Against the background of treatment, it is not recommended to prescribe other analogs of the drug due to the appearance of the risk of hypercalcemia.

Terms of sale

You dont need a prescription to buy Alpha D3 Teva.

Storage conditions

At a temperature not exceeding 25 ° C.Shelf life - 36 months/

Reviews of Alpha D3-Teva

Numerous reviews about Alpha D3-Teva on the forums indicate its high effectiveness in adults and children. A pronounced effect is noted especially in elderly patients with fractures of the upper and lower extremities, taking the drug in the recovery period, as well as in the treatment of osteoporosis in patients over 60 years of age.The high efficiency of Alpha D3-Teva is also noted by parents of children suffering from rickets. The course of the drug significantly improves the condition of the musculoskeletal system of the child.